A drop of serum running down a large green leaf
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Why ceramides come in a 3:1:1 ratio

Why ceramides come in a 3:1:1 ratio

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by Sera Editorial

Reading time: 4 minutes

The outer layer of skin is often described as bricks and mortar. The bricks are skin cells. The mortar is a mix of lipids that keeps water in and irritants out. When that mortar thins, skin feels tight, flakes and stings.

Close-up of dry skin texture

What the mortar is made of

Lipid Share of the mortar
Ceramides Roughly half
Cholesterol About a quarter
Free fatty acids The rest

Put those three back in similar proportions and the skin can rebuild its barrier more easily than with ceramides alone.

A swatch of rich cream

The 3:1:1 ratio

Barrier Cream uses three ceramides with cholesterol and linoleic acid, balanced in a 3:1:1 ratio.

  • Ceramide NP, AP and EOP, three of the ceramide types found in skin
  • Cholesterol, to keep the lipid layer flexible
  • Linoleic acid, a fatty acid that completes the mix

It is the same logic behind many barrier creams used after procedures, adapted for daily use.

Why the ratio matters: a cream with ceramides alone gives skin one part of the mortar. A balanced mix gives it all three.

Who needs it

  • Dry or flaky skin, especially in winter
  • Skin that stings when you apply products
  • Anyone using retinal or acids
  • Skin that has been over-exfoliated

How to use ceramides

  1. Morning: apply on slightly damp skin as the last step before sunscreen.
  2. Night: apply as the last step of your routine.
  3. Body: Ceramide Body Lotion follows the same idea at a lighter texture.

Frequently asked questions

Can I use Barrier Cream with retinal?

Yes, and it is a good pairing. Apply it straight after retinal, or before it if your skin is sensitive.

Why apply on damp skin?

A cream applied on slightly damp skin helps hold that water in, so skin feels softer for longer.

Is it suitable for oily skin?

Oily skin can still have a weak barrier. If your skin is oily but tight or stinging, a thin layer at night is a good place to start.

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